Proliant Health & Biologicals specializes in the development of ingredients from natural sources for the human health and nutrition industry, including the dietary supplement, clinical nutrition, consumer health and functional food markets. We use exciting new technologies to isolate bio-active proteins and peptides that play vital roles in human health. The most well-known of these are immunoglobulins.

Our ingredients are unsurpassed in innovation and quality, which allows them to be used in the most sensitive nutritional applications. ImmunoLin® is an immunoglobulin protein isolate which can be used for tablets, capsules, drink mixes, lozenges and bars. NutraGammax^TM is a serum protein isolate suitable for drink mixes, bars, and various other nutritional products.

The central role of immunoglobulin in providing immunological protection is very well established. Immunoglobulin, or antibodies, is also known to be the critical, bioactive component of milk or colostrum that confers immunity to the neonate in the process called passive immunity. The function of immunoglobulin in the digestive tract in its passive immunity role is to bind to a foreign molecule, such as at the surface of a bacteria or a toxin so that the molecule can be removed from the digestive tract without stimulation of the immune system. This process of removing antigens is called immune exclusion.

A recent study will make the industry re-consider perceptions on proteins and cholesterol. A double-blind, placebo-controlled study with the objective of examining the effectiveness of oral supplementation of ImmunoLin® on lipid indices in hypercholesterolemic humans (N = 52) was reported at Experimental Biology in 2004. Consumption of 5 grams per day of ImmunoLin® for just 3 or 6 weeks reduced both total and LDL cholesterol compared to baseline measures. The change in both total and LDL cholesterol was also greater than the change observed in volunteers receiving the placebo after 6 weeks. Thus, ImmunoLin® supplementation also appears to positively modulate major lipid indices associated with cardiovascular disease.

Studies have shown that when IGF-I and TNF-α are added together, TNF-α greatly impairs the ability of IGF-I to promote protein synthesis. With the use of NutraGammax^TM, TNF-α is inhibited and IGF-1 is able to promote protein synthesis. The use of ImmunoLin® and NutraGammax^TM to modulate the immune response is patent-pending. NutraGammax^TM is a protein uniquely different from whey. It has a much higher molecular weight and has slow-release characteristics making a combination of whey and NutraGammax^TM very complimentary.

ImmunoLin® and NutraGammax^TM are relatively new ingredients to the human health and nutrition industry with an expanding clinical base supporting their use. Because ImmunoLin® can positively effect immune function and lower cholesterol, it has tremendous potential in immune, digestive health and cardiovascular formulas. NutraGammax^TM increases protein efficiency, increases lean tissue growth and reduces inflammatory cytokine levels., thus, increasing lean body mass, stronger immunity and faster recovery.