New Research Establishes EC50 Values for Norwegian Spruce Lignans (HMRlignan) Efficacy In Managing Menopause

New Research Establishes EC50 Values for Norwegian Spruce Lignans (HMRlignan) Efficacy In Managing Menopause
Home Naturade Significantly Strengthens Balance Sheet; Receives $2.5 Million in Capital from Westgate Equity Partners, L.P. Natrol Appoints Vincent Andrich VP Sales for Prolab Division Vermont Pure Holdings, Ltd. Announces Record Fiscal Year 2001 Results Body Shop Reports 24.8 Mil Euro Sales Revenues Spectrum Organic Products Responds to FDA Letter Regarding Use of Non-GMO Seal on Canola Oil Label Supplement Group Targets Consumer Education Advanced Nutraceuticals, Inc. Announces 2001 Year End Results And Additional Financing ADM Awarded Nutraceuticals Patent Patent Creates Proprietary Position for ADM in Fast-Growing Nutraceutical Market Tantivy Sciences Obtains Exclusive License to Unique Nutraceutical Products Top GNC Executives Tour Pittsburgh Market to Present New Business Plan and Expansion Possibilities; Meeting will focus on new business strategies and growth Nutrition 21 Receives Patent For the Nutritional Treatment of Type 2 Diabetes; Patent Presents New Pharmaceutical Licensing Opportunities ConsumerLab.com Finds Most B-vitamin Supplements Contain What They Claim, But Often Exceed Safe Levels - Consumers Cautioned to Be Aware of Side Effects with High Dose Products Nutraceutix, Inc., Nutravite Announcement Commercial Availability of CDT™ Glucosamine for Canadian Marketplace Harvey Kamil Appointed President of NBTY, Inc. - Scott Rudolph to Continue as Chairman and CEO drugstore.com Expects to Reach Profitability Target in 2003 Human Genome Project Leads to Innovative Healthcare NPIcenter’s Career Center targets nutraceutical Industry Adding Vitamin C To Certain Drugs May Help Treat Alzheimer's, Other Brain Disorders Adding Vitamin C To Certain Drugs May Help Treat Alzheimer's, Other Brain Disorders Editorial: An Exercise in Synergy NBTY, Inc. Appoints Harvey Kamil President, Scott Rudolph To Continue As Chairman And CEO Ross Products to Launch Infant Formula Supplemented With Two New Fatty Acids Ross Products to Launch Infant Formula Supplemented With Two New Fatty Acids Ross Products to Launch Infant Formula Supplemented With Two New Fatty Acids LignisulMSM vs Naproxen for Osteoarthritis Clinical Trial Gets Underway Natural Health Trends Corp. Launches Lexxus Taiwan FDA Presents Compliance Guide for Structure/Function Claims New TrimFit® Bars Redefine Energy Bar Category New TrimFit® Bars Redefine Energy Bar Category Probiata® Offers Safe, Natural and Effective Alternative Alive & Well with Michelle Harris Be Well and Get Rewarded! Find Personalized Wellness Solutions and Earn Free Vitamins at NatureMade.com Consumers Search for Healthy Cleaning Products That Work Nordic Naturals: Omega 3 Fatty Acids Cyanotech Names Bob Capelli as Director of Sales Planet Dog Parnters With Training Expert Jennifer McCarthy, known as "The Dog Trainer to the Stars", has joined forces with Planet Dog to assist in the development of new products and product testing for the socially responsible designer, manufacturer and retailer. Planet Dog Parnters With Training Expert Jennifer McCarthy, known as "The Dog Trainer to the Stars", has joined forces with Planet Dog to assist in the development of new products and product testing for the socially responsible designer, manufacturer and retailer. Planet Dog Parnters With Training Expert Jennifer McCarthy, known as "The Dog Trainer to the Stars", has joined forces with Planet Dog to assist in the development of new products and product testing for the socially responsible designer, manufacturer and retailer. AOAC International Call for Dietary Supplement Ingredients That Need Validated Analytical Methods AOAC International, a worldwide provider and facilitator in the development of analytical standards, is issuing a call for dietary supplement ingredients in order to prioritize those ingredients that need validated methods. Interested parties are invited to submit ingredients by April 14, 2006, with a brief justification/need statement as to why these ingredients should be considered. AOAC International Call for Dietary Supplement Ingredients That Need Validated Analytical Methods AOAC International, a worldwide provider and facilitator in the development of analytical standards, is issuing a call for dietary supplement ingredients in order to prioritize those ingredients that need validated methods. Interested parties are invited to submit ingredients by April 14, 2006, with a brief justification/need statement as to why these ingredients should be considered. AOAC International Call for Dietary Supplement Ingredients That Need Validated Analytical Methods AOAC International, a worldwide provider and facilitator in the development of analytical standards, is issuing a call for dietary supplement ingredients in order to prioritize those ingredients that need validated methods. Interested parties are invited to submit ingredients by April 14, 2006, with a brief justification/need statement as to why these ingredients should be considered. AOAC International Call for Dietary Supplement Ingredients That Need Validated Analytical Methods AOAC International, a worldwide provider and facilitator in the development of analytical standards, is issuing a call for dietary supplement ingredients in order to prioritize those ingredients that need validated methods. Interested parties are invited to submit ingredients by April 14, 2006, with a brief justification/need statement as to why these ingredients should be considered. PeptoPro Goes Sonic Proteinfactory.com launches advanced formula Sonic Protein, a powdered beverage which uses DSM's unique PeptoPro(tm) casein hydrolysates to reach the body's muscles faster than other proteins, delivering significant benefits pre- and post-workout. PeptoPro Goes Sonic Proteinfactory.com launches advanced formula Sonic Protein, a powdered beverage which uses DSM's unique PeptoPro(tm) casein hydrolysates to reach the body's muscles faster than other proteins, delivering significant benefits pre- and post-workout. PeptoPro Goes Sonic Proteinfactory.com launches advanced formula Sonic Protein, a powdered beverage which uses DSM's unique PeptoPro(tm) casein hydrolysates to reach the body's muscles faster than other proteins, delivering significant benefits pre- and post-workout. PeptoPro Goes Sonic Proteinfactory.com launches advanced formula Sonic Protein, a powdered beverage which uses DSM's unique PeptoPro(tm) casein hydrolysates to reach the body's muscles faster than other proteins, delivering significant benefits pre- and post-workout. PeptoPro Goes Sonic Proteinfactory.com launches advanced formula Sonic Protein, a powdered beverage which uses DSM's unique PeptoPro(tm) casein hydrolysates to reach the body's muscles faster than other proteins, delivering significant benefits pre- and post-workout. PeptoPro Goes Sonic Proteinfactory.com launches advanced formula Sonic Protein, a powdered beverage which uses DSM's unique PeptoPro(tm) casein hydrolysates to reach the body's muscles faster than other proteins, delivering significant benefits pre- and post-workout. PeptoPro Goes Sonic Proteinfactory.com launches advanced formula Sonic Protein, a powdered beverage which uses DSM's unique PeptoPro(tm) casein hydrolysates to reach the body's muscles faster than other proteins, delivering significant benefits pre- and post-workout. SPINS' Natural Product Opportunity Report first to demonstrate Natural Products' performance and share of retail at the category level Sales of Natural and Organic Products have increased 18% over 2004, surpassing Conventional Product sales growth of 2-3%; segment holds an untapped growth opportunity of at least $3.6B. SPINS' Natural Product Opportunity Report first to demonstrate Natural Products' performance and share of retail at the category level Sales of Natural and Organic Products have increased 18% over 2004, surpassing Conventional Product sales growth of 2-3%; segment holds an untapped growth opportunity of at least $3.6B. SPINS' Natural Product Opportunity Report first to demonstrate Natural Products' performance and share of retail at the category level Sales of Natural and Organic Products have increased 18% over 2004, surpassing Conventional Product sales growth of 2-3%; segment holds an untapped growth opportunity of at least $3.6B. AMERICAN BIOSCIENCES WINS AWARD for their Introduction of AVÉ to the U.S American BioSciences: Selected by NUTRACON’s Experts as finalist for the coveted NutrAward American BioSciences: Selected by NUTRACON’s Experts as finalist for the coveted NutrAward IMG's Hilton to Lead Brand Building Workshop Series in Canada Jeff Hilton has been invited to direct a two-phase workshop series entitled, "Strategies for Effective Brand Building." Canada's British Columbia Functional Food and Nutraceutical Network (BCFN) and the British Columbia Food Processor's Association selected Hilton to lead sessions examining the branding process from both theroretical and practical perspectives. IMG's Hilton to Lead Brand Building Workshop Series in Canada Jeff Hilton has been invited to direct a two-phase workshop series entitled, "Strategies for Effective Brand Building." Canada's British Columbia Functional Food and Nutraceutical Network (BCFN) and the British Columbia Food Processor's Association selected Hilton to lead sessions examining the branding process from both theroretical and practical perspectives. IMG's Hilton to Lead Brand Building Workshop Series in Canada Jeff Hilton has been invited to direct a two-phase workshop series entitled, "Strategies for Effective Brand Building." Canada's British Columbia Functional Food and Nutraceutical Network (BCFN) and the British Columbia Food Processor's Association selected Hilton to lead sessions examining the branding process from both theroretical and practical perspectives. IMG's Hilton to Lead Brand Building Workshop Series in Canada Jeff Hilton has been invited to direct a two-phase workshop series entitled, "Strategies for Effective Brand Building." Canada's British Columbia Functional Food and Nutraceutical Network (BCFN) and the British Columbia Food Processor's Association selected Hilton to lead sessions examining the branding process from both theroretical and practical perspectives. IMG's Hilton to Lead Brand Building Workshop Series in Canada Jeff Hilton has been invited to direct a two-phase workshop series entitled, "Strategies for Effective Brand Building." Canada's British Columbia Functional Food and Nutraceutical Network (BCFN) and the British Columbia Food Processor's Association selected Hilton to lead sessions examining the branding process from both theroretical and practical perspectives. Keratec's new skin health ingredient bridges cosmetics and supplements Skincare ingredient bridges the gap between topical coismetics and dietary supplements - ingredients in the range include Cynergy TK(TM) and Cynergy NK(TM). Keratec's new skin health ingredient bridges cosmetics and supplements Skincare ingredient bridges the gap between topical coismetics and dietary supplements - ingredients in the range include Cynergy TK(TM) and Cynergy NK(TM). Keratec's new skin health ingredient bridges cosmetics and supplements Skincare ingredient bridges the gap between topical coismetics and dietary supplements - ingredients in the range include Cynergy TK(TM) and Cynergy NK(TM). Keratec's new skin health ingredient bridges cosmetics and supplements Skincare ingredient bridges the gap between topical coismetics and dietary supplements - ingredients in the range include Cynergy TK(TM) and Cynergy NK(TM). Keratec's new skin health ingredient bridges cosmetics and supplements Skincare ingredient bridges the gap between topical coismetics and dietary supplements - ingredients in the range include Cynergy TK(TM) and Cynergy NK(TM). Ocean Nutrition Canada introduces Powder-locT M) microencapsulation technology Ocean Nutrition Canada introduces Powder-locT M) microencapsulation technology Denomega Nutritional Oils and GAT Food Essentials Announce Exclusive OMEGA-3 Co-branding Agreement Denomega Nutritional Oils (Denomega) and GAT Food Essentials (GAT) announced today agreements committing the parties to work closely together in the Omega-3 functional food and beverage markets. The agreements are effective March 23, 2006. Denomega Nutritional Oils and GAT Food Essentials Announce Exclusive OMEGA-3 Co-branding Agreement Denomega Nutritional Oils (Denomega) and GAT Food Essentials (GAT) announced today agreements committing the parties to work closely together in the Omega-3 functional food and beverage markets. The agreements are effective March 23, 2006. Denomega Nutritional Oils and GAT Food Essentials Announce Exclusive OMEGA-3 Co-branding Agreement Denomega Nutritional Oils (Denomega) and GAT Food Essentials (GAT) announced today agreements committing the parties to work closely together in the Omega-3 functional food and beverage markets. The agreements are effective March 23, 2006. Natural Cosmetics Sales Booming in France Natural Cosmetics Sales Booming in France Colgate Purchasing Tom’s of Maine - Enters Fast-Growing Natural Products Segment The transaction will be structured as an all cash acquisition of 84 percent of the outstanding shares of Tom’s of Maine for an aggregate price of approximately $100 million, subject to adjustment at closing, with the Chappell family continuing to hold a 16% stake. Colgate Purchasing Tom’s of Maine - Enters Fast-Growing Natural Products Segment The transaction will be structured as an all cash acquisition of 84 percent of the outstanding shares of Tom’s of Maine for an aggregate price of approximately $100 million, subject to adjustment at closing, with the Chappell family continuing to hold a 16% stake. Colgate Purchasing Tom’s of Maine - Enters Fast-Growing Natural Products Segment The transaction will be structured as an all cash acquisition of 84 percent of the outstanding shares of Tom’s of Maine for an aggregate price of approximately $100 million, subject to adjustment at closing, with the Chappell family continuing to hold a 16% stake. New Peer-reviewed Studies Highlight Positive Health Benefits of Natural Resistant Starch Company notes that since the beginning of 2005 alone, there have been 15 studies published on the health benefits of natural resistant starches around the world. New Peer-reviewed Studies Highlight Positive Health Benefits of Natural Resistant Starch Company notes that since the beginning of 2005 alone, there have been 15 studies published on the health benefits of natural resistant starches around the world. New Peer-reviewed Studies Highlight Positive Health Benefits of Natural Resistant Starch Company notes that since the beginning of 2005 alone, there have been 15 studies published on the health benefits of natural resistant starches around the world. New Peer-reviewed Studies Highlight Positive Health Benefits of Natural Resistant Starch Company notes that since the beginning of 2005 alone, there have been 15 studies published on the health benefits of natural resistant starches around the world. New Peer-reviewed Studies Highlight Positive Health Benefits of Natural Resistant Starch Company notes that since the beginning of 2005 alone, there have been 15 studies published on the health benefits of natural resistant starches around the world. Event: Challenge of China: Critical Issues for Network Marketing, Direct Sales and Dietary Supplement Companies Event: Challenge of China: Critical Issues for Network Marketing, Direct Sales and Dietary Supplement Companies Event: Challenge of China: Critical Issues for Network Marketing, Direct Sales and Dietary Supplement Companies Event: Challenge of China: Critical Issues for Network Marketing, Direct Sales and Dietary Supplement Companies Event: Challenge of China: Critical Issues for Network Marketing, Direct Sales and Dietary Supplement Companies InterHealth Names New Vice President Company announces the appointment of Daniel Murray, a 20-year veteran of the food manufacturing industry, as vice president of sales - food and beverage, to lead strategic business development efforts of the company’s growing functional food and beverage division. InterHealth Names New Vice President Company announces the appointment of Daniel Murray, a 20-year veteran of the food manufacturing industry, as vice president of sales - food and beverage, to lead strategic business development efforts of the company’s growing functional food and beverage division. InterHealth Names New Vice President Company announces the appointment of Daniel Murray, a 20-year veteran of the food manufacturing industry, as vice president of sales - food and beverage, to lead strategic business development efforts of the company’s growing functional food and beverage division. InterHealth Names New Vice President Company announces the appointment of Daniel Murray, a 20-year veteran of the food manufacturing industry, as vice president of sales - food and beverage, to lead strategic business development efforts of the company’s growing functional food and beverage division. InterHealth Names New Vice President Company announces the appointment of Daniel Murray, a 20-year veteran of the food manufacturing industry, as vice president of sales - food and beverage, to lead strategic business development efforts of the company’s growing functional food and beverage division. InterHealth Names New Vice President Company announces the appointment of Daniel Murray, a 20-year veteran of the food manufacturing industry, as vice president of sales - food and beverage, to lead strategic business development efforts of the company’s growing functional food and beverage division. InterHealth Names New Vice President Company announces the appointment of Daniel Murray, a 20-year veteran of the food manufacturing industry, as vice president of sales - food and beverage, to lead strategic business development efforts of the company’s growing functional food and beverage division. InterHealth Names New Vice President Company announces the appointment of Daniel Murray, a 20-year veteran of the food manufacturing industry, as vice president of sales - food and beverage, to lead strategic business development efforts of the company’s growing functional food and beverage division. Natural Products Expo West Breaks Attendance and Exhibit Records More than 43,000 industry attendees learned about the newest products for health-seeking consumers. Natural Products Expo West Breaks Attendance and Exhibit Records More than 43,000 industry attendees learned about the newest products for health-seeking consumers. Natural Products Expo West Breaks Attendance and Exhibit Records More than 43,000 industry attendees learned about the newest products for health-seeking consumers. Natural Products Expo West Breaks Attendance and Exhibit Records More than 43,000 industry attendees learned about the newest products for health-seeking consumers. Natural Products Expo West Breaks Attendance and Exhibit Records More than 43,000 industry attendees learned about the newest products for health-seeking consumers. Quality Standards Issued for Testing Herbal Products The new NIST reference materials were designed primarily for quality control of supplements containing ephedra, with NIST asserting that the standards remain valuable to ensure products are not adulterated with ephedra or to improve measurements of impurities such as heavy metals. Quality Standards Issued for Testing Herbal Products The new NIST reference materials were designed primarily for quality control of supplements containing ephedra, with NIST asserting that the standards remain valuable to ensure products are not adulterated with ephedra or to improve measurements of impurities such as heavy metals. Quality Standards Issued for Testing Herbal Products The new NIST reference materials were designed primarily for quality control of supplements containing ephedra, with NIST asserting that the standards remain valuable to ensure products are not adulterated with ephedra or to improve measurements of impurities such as heavy metals. Quality Standards Issued for Testing Herbal Products The new NIST reference materials were designed primarily for quality control of supplements containing ephedra, with NIST asserting that the standards remain valuable to ensure products are not adulterated with ephedra or to improve measurements of impurities such as heavy metals. SOALJO SRL Launches an Exclusive Line of South American Standardized Herbal Extracts Argentina-based ingredient supplier SOALJO SRL is commencing marketing in the USA of the company's exclusive and innovative line of South American herbal extracts. SOALJO SRL Launches an Exclusive Line of South American Standardized Herbal Extracts Argentina-based ingredient supplier SOALJO SRL is commencing marketing in the USA of the company's exclusive and innovative line of South American herbal extracts. SOALJO SRL Launches an Exclusive Line of South American Standardized Herbal Extracts Argentina-based ingredient supplier SOALJO SRL is commencing marketing in the USA of the company's exclusive and innovative line of South American herbal extracts. Frost & Sullivan Honours GAT Food Essentials GmbH With European Functional Food & Beverage Microencapsulation Technology Innovation Award The 2009 Frost & Sullivan European Functional Food & Beverage Microencapsulation Technology Innovation Award has been presented to GAT Food Essentials GmbH in recognition of its proprietary wowCAPS(R) technology. Frost & Sullivan Honours GAT Food Essentials GmbH With European Functional Food & Beverage Microencapsulation Technology Innovation Award The 2009 Frost & Sullivan European Functional Food & Beverage Microencapsulation Technology Innovation Award has been presented to GAT Food Essentials GmbH in recognition of its proprietary wowCAPS(R) technology. Frost & Sullivan Honours GAT Food Essentials GmbH With European Functional Food & Beverage Microencapsulation Technology Innovation Award The 2009 Frost & Sullivan European Functional Food & Beverage Microencapsulation Technology Innovation Award has been presented to GAT Food Essentials GmbH in recognition of its proprietary wowCAPS(R) technology. BioExx Achieves Self-Affirmed GRAS Status for Protein Isolates Bio-Extraction Inc., has announced that it has completed the self-affirmation process to qualify its specialty canola protein products, Isolexx(TM) and Vitalexx(TM), as self-affirmed GRAS for their intended use in various foods and beverages, thus providing a basis for the sale of these products in the United States when commercial production commences in Q1 2010. BioExx Achieves Self-Affirmed GRAS Status for Protein Isolates Bio-Extraction Inc., has announced that it has completed the self-affirmation process to qualify its specialty canola protein products, Isolexx(TM) and Vitalexx(TM), as self-affirmed GRAS for their intended use in various foods and beverages, thus providing a basis for the sale of these products in the United States when commercial production commences in Q1 2010. BioExx Achieves Self-Affirmed GRAS Status for Protein Isolates Bio-Extraction Inc., has announced that it has completed the self-affirmation process to qualify its specialty canola protein products, Isolexx(TM) and Vitalexx(TM), as self-affirmed GRAS for their intended use in various foods and beverages, thus providing a basis for the sale of these products in the United States when commercial production commences in Q1 2010. BioExx Achieves Self-Affirmed GRAS Status for Protein Isolates Bio-Extraction Inc., has announced that it has completed the self-affirmation process to qualify its specialty canola protein products, Isolexx(TM) and Vitalexx(TM), as self-affirmed GRAS for their intended use in various foods and beverages, thus providing a basis for the sale of these products in the United States when commercial production commences in Q1 2010. BioExx Achieves Self-Affirmed GRAS Status for Protein Isolates Bio-Extraction Inc., has announced that it has completed the self-affirmation process to qualify its specialty canola protein products, Isolexx(TM) and Vitalexx(TM), as self-affirmed GRAS for their intended use in various foods and beverages, thus providing a basis for the sale of these products in the United States when commercial production commences in Q1 2010. BioExx Achieves Self-Affirmed GRAS Status for Protein Isolates Bio-Extraction Inc., has announced that it has completed the self-affirmation process to qualify its specialty canola protein products, Isolexx(TM) and Vitalexx(TM), as self-affirmed GRAS for their intended use in various foods and beverages, thus providing a basis for the sale of these products in the United States when commercial production commences in Q1 2010. BioExx Achieves Self-Affirmed GRAS Status for Protein Isolates Bio-Extraction Inc., has announced that it has completed the self-affirmation process to qualify its specialty canola protein products, Isolexx(TM) and Vitalexx(TM), as self-affirmed GRAS for their intended use in various foods and beverages, thus providing a basis for the sale of these products in the United States when commercial production commences in Q1 2010. BioExx Achieves Self-Affirmed GRAS Status for Protein Isolates Bio-Extraction Inc., has announced that it has completed the self-affirmation process to qualify its specialty canola protein products, Isolexx(TM) and Vitalexx(TM), as self-affirmed GRAS for their intended use in various foods and beverages, thus providing a basis for the sale of these products in the United States when commercial production commences in Q1 2010. BioExx Achieves Self-Affirmed GRAS Status for Protein Isolates Bio-Extraction Inc., has announced that it has completed the self-affirmation process to qualify its specialty canola protein products, Isolexx(TM) and Vitalexx(TM), as self-affirmed GRAS for their intended use in various foods and beverages, thus providing a basis for the sale of these products in the United States when commercial production commences in Q1 2010. Synergy Flavors Invests in Sensory Flavor Profiling Research Synergy Flavors has commissioned a new research program at North Carolina State University to study the sensory profiles of a range of protein ingredients. Synergy Flavors Invests in Sensory Flavor Profiling Research Synergy Flavors has commissioned a new research program at North Carolina State University to study the sensory profiles of a range of protein ingredients. Synergy Flavors Invests in Sensory Flavor Profiling Research Synergy Flavors has commissioned a new research program at North Carolina State University to study the sensory profiles of a range of protein ingredients. Synergy Flavors Invests in Sensory Flavor Profiling Research Synergy Flavors has commissioned a new research program at North Carolina State University to study the sensory profiles of a range of protein ingredients. Synergy Flavors Invests in Sensory Flavor Profiling Research Synergy Flavors has commissioned a new research program at North Carolina State University to study the sensory profiles of a range of protein ingredients. Beat Crazy Cocoa Prices with Synergy's Chocolate Flavors Synergy Flavors Inc., has announced their chocolate flavors offer a versatile solution for cocoa reduction and can be used as cocoa extenders. Beat Crazy Cocoa Prices with Synergy's Chocolate Flavors Synergy Flavors Inc., has announced their chocolate flavors offer a versatile solution for cocoa reduction and can be used as cocoa extenders. Beat Crazy Cocoa Prices with Synergy's Chocolate Flavors Synergy Flavors Inc., has announced their chocolate flavors offer a versatile solution for cocoa reduction and can be used as cocoa extenders. Beat Crazy Cocoa Prices with Synergy's Chocolate Flavors Synergy Flavors Inc., has announced their chocolate flavors offer a versatile solution for cocoa reduction and can be used as cocoa extenders. Beat Crazy Cocoa Prices with Synergy's Chocolate Flavors Synergy Flavors Inc., has announced their chocolate flavors offer a versatile solution for cocoa reduction and can be used as cocoa extenders. Beat Crazy Cocoa Prices with Synergy's Chocolate Flavors Synergy Flavors Inc., has announced their chocolate flavors offer a versatile solution for cocoa reduction and can be used as cocoa extenders. Beat Crazy Cocoa Prices with Synergy's Chocolate Flavors Synergy Flavors Inc., has announced their chocolate flavors offer a versatile solution for cocoa reduction and can be used as cocoa extenders. NPI Daily - Top of The News for Nov. 20, 2009 - FDA Issues 22 Warning Letters to Website Operators Frost & Sullivan Honours GAT Food Essentials GmbH With European Functional Food & Beverage Microencapsulation Technology Innovation Award; Synergy Flavors Invests in Sensory Flavor Profiling Research; FDA Issues 22 Warning Letters to Website Operators; Nordic Naturals Ultimate Omega™ First Fish Oil to Participate in NFL/NFLPA Sports Nutrition Label Certification Program; BioExx Achieves Self-Affirmed GRAS Status for Protein Isolates; New Organic Berry Whole Food Energy Bar from Amazing Grass Delivers Whole Food Nutrition; Beat Crazy Cocoa Prices with Synergy's Chocolate Flavors NPI Daily - Top of The News for Nov. 20, 2009 - FDA Issues 22 Warning Letters to Website Operators Frost & Sullivan Honours GAT Food Essentials GmbH With European Functional Food & Beverage Microencapsulation Technology Innovation Award; Synergy Flavors Invests in Sensory Flavor Profiling Research; FDA Issues 22 Warning Letters to Website Operators; Nordic Naturals Ultimate Omega™ First Fish Oil to Participate in NFL/NFLPA Sports Nutrition Label Certification Program; BioExx Achieves Self-Affirmed GRAS Status for Protein Isolates; New Organic Berry Whole Food Energy Bar from Amazing Grass Delivers Whole Food Nutrition; Beat Crazy Cocoa Prices with Synergy's Chocolate Flavors Heart Health Alert: Niacin May Reverse Hardening of the Arteries Heart Health Alert: Niacin May Reverse Hardening of the Arteries Heart Health Alert: Niacin May Reverse Hardening of the Arteries Heart Health Alert: Niacin May Reverse Hardening of the Arteries Spotlight on Savory Side Dishes Spotlight on Savory Side Dishes Spotlight on Savory Side Dishes Another Reason to Choose Healthy Lifestyle Habits Another Reason to Choose Healthy Lifestyle Habits	Study confirms 10mg - 30 mg dose for lignan supplement ANAHEIM, CA – March 24, 2006 – New research performed by the clinical medicine faculty at the University of Insubria in Italy has added to the body of evidence supporting the use of lignan phytoestrogens to help women manage menopause. In the study, designed to establish the effective median concentration value (EC50) of Norway spruce-derived lignan, hydroxymatairesinol and its human metabolite enterolactone in comparison to estradiol, experiments confirmed a daily dosage 10 mg – 30 mg as sufficient to raise circulating enterolactone to estrogenically active levels. In the study, in which all three compounds displayed estrogenic activity in the MCF-7 breast cell model, estradiol displayed the highest potency in the pM concentration range whilst enterolactone exerted activity in the same concentration range as estradiol but with far less efficacy (about 2/5 that of estradiol). Hydroxymatairesinol exhibited a significantly lower efficacy (about 7/10 that of estradiol) but only in the microM concentration range. The study concluded that both hydroxymatairesinol and its metabolite enterolactone are endowed with estrogenic activity, which is likely to be exerted through estrogen receptors and to target the same intracellular mechanisms acted upon by estradiol. The estrogenicity of hydroxymatairesinol and enterolactone is however milder than that of estradiol, as indicated by the lower potencies and efficacies of both lignans. Commenting on the significance of the study the lead research pharmacologist, Dr. Marco Cosentino, stated, ‘The present results support the notion that dietary supplementation with Norway spruce lignans provides a suitable source for endogenous enterolactone which in turn is likely beneficial for several conditions related to estrogen insufficiency (e.g., bone, and cardiovascular disturbances, as well as menopause-associated symptoms), and at the same time devoid of the adverse effects induced by stronger estrogenic agents. Bioavailability studies in humans show that, after oral supplementation with Norway spruce lignans, plasma concentrations of hydroxymatairesinol and enterolactone occur in the sub-microM range, which are below the observed in vitro EC50 (effective median concentration) of hydroxymatairesinol but well above the EC50 of enterolactone. Therefore, in humans, hydroxymatairesinol at the currently recommended doses represent mainly a source of enterolactone, which in turn exerts a mild estrogenic activity. “This is great news for women offering a soft phytoestrogen alternative to help manage menopause,” adds Don Stanek, Director of Sales for Linnea Inc. “HMRlignan™ offers a highly bioavailable and efficient method to boost enterolactone levels. In human pharmacokinetic studies just 10 mg - 30 mg of HMRLignan™ has been demonstrated to maintain enterolactone above the EC50 levels established in this study.” Derived from Norway spruce (Picea abies) HMRlignan™ is a direct enterolactone precursor dietary supplement standardized to contain 80,000 mg/100 g of lignans. It is a proprietary and patent protected product developed in Finland by Hormos Medical Corporation, and manufactured and marketed worldwide under license by Linnea, Switzerland. About Linnea From its headquarters and manufacturing facility in Locarno, Switzerland, Linnea specializes in the manufacture of botanical extracts and phytochemicals, and is a leading supplier to the pharmaceutical, dietary supplement and cosmetic industries. HMRlignan™ is a proprietary, patent protected, product manufactured by Linnea SA. The company’s U.S. office, Linnea Inc., is located in Easton, Pennsylvania. For more information about HMRlignan™, visit our Web site at www.hmrlignan.com or call 1-888-253-0044.
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